Have you ever encountered this situation? Let me introduce you to two patients in my practice.

Caroline is a healthy, 23-year-old patient. She has a retained primary lateral incisor at tooth #10 position that is decalcified and un esthetic The tooth has undergone bone replacement root resorption.

As a result, the tooth is ankylosed, but has acceptable bone and adequate facial prominence. An immediate implant and immediate provisional is considered the ideal treatment for replacement.

immediate implant placement


delayed implant loading reasons

Karen is 64 years old and her medical history is non-contributory. She, too, requires an implant at tooth #10 because of tooth fracture from mastication. The existing tooth was deemed non-restorable. There is no periapical infection and a healthy periodontium. An implant was treatment planned as the replacement. 

immediate implant placement
dental x ray before implant loading

Both Caroline and Karen’s lateral incisors were removed, and immediate implants were placed. Although the implant surgeons were different, they were both long-time members of my Interdisciplinary team and have significant implant placement experience. Both implants were torqued to 50 Ncm at the time of placement. Provisionals were then placed, by me, that same day.

The implants were not in occlusion and instructions for mastication and maintenance were provided. Neither patient wore occlusal appliances or night guards. However, Caroline routinely wore Essex retainers, provided by her orthodontist. I had fabricated a new Essex following her implant provisional. Both implants were allowed to heal for four months prior to final restoration

provisional implant restoration
post implant x ray

Following four months of healing, Karen was appointed in my office for final restoration of the implant. The provisional was removed, without anesthesia, and the implant impression post was secured to the newly healed implant. The restorative process was uneventful, and a ceramic restoration and gold post were placed.


Alternatively, Caroline was scheduled for her implant restorative process. Again, no anesthesia was utilized. The retaining screw was loosened and the provisional removed. Upon tightening the impression post to the implant, Caroline winced with pain! The implant was not integrated! Why?

In this scenario, there are two separate implants with perfect indications for immediate extraction, immediate implant placement and immediate provisionalization, both placed by experienced and competent surgeons. Why does one implant integrate and the other not? These situations are very frustrating for both doctor and patient. An understanding of the biology and biomechanics of healing implants may shed some light and provide some guidance for these cases.

implant attachment

Biology of Implants

“Osseointegration” is the term applied to the healed implant/bone interface. It is described as “the direct structural and functional connection between ordered bone and the surface of a load-bearing implant.” The two key words in this sentence are “structural” (bone/static) and “functional” (implant/dynamic). These two aspects of integration are key to implant stability and longevity.

The process of placing implants involves the cutting and drilling of the bone. Adequate cooling from water spray and proper speed of osteotomy are essential for reducing the trauma to the cells. The goal is to create intimate contact between the implant and the bony walls of the osteotomy.

This intimacy is referred to as the bone-to-implant contact. It is a function of both the implant length and diameter (BIC). This intimate contact provides the primary stability of the implant. Acceptable stability is verified through the torque testing at the time of placement. 50Ncm or greater torque is considered acceptable for immediate loading of the implant.

Regardless of the BIC, micro and mini “gaps” exist at the bone/implant interface. These “gaps” fill with blood and ultimately form clots. Ideally, bone will replace these clots through a process of resorption/replacement. The oxidized layer of the titanium implant creates a cellular response that promotes adhesion and cellular proliferation. This is the “structural” component of healing implants. The “static” aspect of primary stability is important to allow adequate healing to occur prior to “loading” of the implant.

The “functional” aspect of implant loading relates to the forces applied to the implant. Although the implant is stabilized at the time of placement, functional forces of occlusion and mastication can be detrimental to adequate healing and bone formation. From a biomechanical standpoint, the type and amount of force applied to the healing implant is critical for successful integration. In biomechanical terms, the implant heals through a “bonding” process to the bone.

Osseointegration of implants

When the implant is fully osseointegrated, it is classified as being “bonded.” “Bonded” implants can accept compression, shearing and tensile forces. Integrated implants are stable. “Un-bonded”, or healing, implants are initially not so stable. They can accept the frictional forces of implant placement and provisional fabrication, but not tensile force.

Excessive implant micro-motion interrupts the vascularity that is essential for proper healing. This interruption may lead to collagen fiber formation around the implant rather than the osseointegration that is desired. Non-axial loading applies significance tensile forces that are detrimental to integration. When we “load” immediately-placed implants through provisionalization, we are introducing “dynamic” forces that can have both positive and negative effects on implant healing.

We know through studies that tissue response to immediate loading can have favorable results in the peri-implant tissues. But care must be taken to not overload the biologic system with functional force!

We can control the forces and manage the micro-motion. There are several options that we have available to do this. The most obvious is to avoid occlusal contact on newly placed provisionalized implants. As stated earlier, vertical forces are a concern, but lateral force is contra-indicated in healing single tooth implants. Splinting multiple implants provides “group” support in resisting implant motion.

The bone quality is also an important factor to evaluate. Type I and II bone (lower and upper anterior regions, respectively) is denser and provides greater initial stabilization of the implant. Type II and IV (posterior regions) is more trabeculated and less dense.

Another factor is implant design and surface texture. Thread design and pitch may increase the area of implant surface for bone contact. The texture of the implant also plays a role. Textured implants increase surface area for bone cell contact better than machined surfaces.

And lastly, implant diameter and length are a significant consideration in implant stability. The longer the implant, the greater the ability of the surgeon to engage bone and achieve primary stability, especially in an immediate extraction - immediate placement scenario. Wider implants provide greater BIC for healing, but implant stability and emergence profiles of the abutment are limitations for a “wider is better” concept. In the end, force management is the key to successful implant integration and longevity!

With these biological and biomechanical factors of implant failure to consider, why would we immediate load? What are the benefits of immediate placement/loading? Is delayed placement/loading better?

Which is more beneficial: delayed or immediate implant placement?

One of the biggest factors of immediate placement is that it decreases treatment time. The healing process of implant therapy is definitive. Depending on all the biologic factors discussed previously, osseointegration occurs slowly. Our patients do not always understand this concept and are not as willing to accept this delay. Patient education is a key factor. Immediate loading certainly increases patient acceptance. Immediate placement of implants at the time of tooth removal maintains optimal soft tissue contours and tissue esthetics.

The emergence profile of the tooth root is more easily captured in the immediate provisional contours, thereby supporting the soft tissues ideally. And, in the absence of infection, the bone response(biology) of the immediate placed implant is favorable.

Delayed placement and loading has its considerations, as well. By delaying placement, tooth site infection may be resolved prior to implant placement. There is a greater percentage of osseointegration in a healed site than an infected site. By delaying the implant placement and allowing the soft tissues to heal, there is better soft tissue volume for surgical flap adaptation and coverage of the implant when it is placed. Additionally, by allowing the surgical site to heal, bone regeneration can occur within the site and improved initial implant stability would be attained.

There are a couple of downsides to delayed placement and loading. Not only is there an increase in treatment time, but there is the potential of bone and tissue resorption that may occur from this delayed approach. Soft tissue contours are critical for esthetic implant success, especially in the anterior. Loss of tissue contour and loss of supporting bone by delaying treatment, may jeopardize the esthetic results of implant tooth replacement.

When deciding upon immediate versus delayed implant placement, many factors must be considered before proceeding in a given direction. A thorough evaluation of the patient's presentation and implant site conditions must be performed. But immediate loading should not be indiscriminate!


biologic cycle implant placement workflow

The diagram of the biologic/biomechanical cycle provides a synopsis of the factors involved in success or failure of immediately placing and loading implants.

Implant osseointegration is a complex process of biology and biomechanics. Immediate implant loading is successful because of a favorable biologic response to stress. Biomechanical design and control of forces on the implant lead to good outcomes. It is not safe to indiscriminately load dental implants. A thorough evaluation of the patient's medical health, dental presentation and overall objectives will aid in determination of implant placement and implant success.

final result implant restoration
final implant restoration
final implant x ray

So, the question remains as to why did Caroline's implant fail? She presented with the ideal circumstance for immediate placement and immediate loading of the implant. All precautions were taken to avoid failure. And yet, osseointegration did not occur. Caroline and her parents were as disappointed as I that implant failure occurred.

But because I could help them understand this biologic and biomechanical process, they were supportive of implant replacement.

The failed implant was removed. A second implant was placed following healing of the site. A provisional was, again, placed on the new implant at the time of placement. Maintenance and care instructions were provided. This implant healed, uneventfully, four months before final restoration. Caroline was very satisfied with this result.

Unfortunately, I do not know why this failure happened. But, by having knowledge and understanding of the implant integration process, we are better able to communicate with our patients and provide guidance as to the direction of treatment and its success.


Mayfield LJA. Immediate, delayed and late submerged and transmucosal implants. In: Lindhe J (ed). Proceedings of the 3rd European Workshop on Periodontology: Implant dentistry. Berlin: Quintessence, 1999: 520-534

Immediate Loading: From biology to biomechanics. Report of the Committee on Research in Fixed Prosthodontics of The American Academy of Fixed Prosthodontics
Peter Barndt, DDS, MS, Hai Zhang, DMD,PhD, Fei Liu, DDS, PhD
Journal of prosthetic Dentistry Vol. 113, #2; February 2015

Serwantanachai,D., et.al. Reference techniques used in bone classification. J of Interdisc Med and Sci. 2015,3:172

Misch, CE. Contemporary Implant Dentistry3rd Ed, .St. Louis; C V Mosby Publishing Co.

Bedrosian, E.,Sullivan, R., Malo, P. J Oral Maxillofac Surg 66:112-122, 2008